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| macroculture -- Overarching cultural structure of a society represented by the cultural aspects that all members of that society share. macrocephaly -- large head size (see picture) macrocytic anemia -- A failure in the oxygen transport system characterized by abnormally large immature red blood cells. macromolecules -- there are four classes of macromolecules that constitute all living matter: carbohydrates, lipids, proteins, and nucleic acids. macroorchidism -- having abnormally large testicles; found in Fragile X syndrome. macrophages -- a type of white blood cell that ingests foreign material. They are key players in the immune response of the body to foreign invaders such as infectious microorganisms. Macrophages help destroy bacteria, protozoa, and tumor cells. macrophobia -- fear of long waits macrosomia -- excessive size and stature at birth; large body size. macrostomia -- large mouth (see crazy picture) macrosystems -- The idealogical, cultural, and institutional contexts that encompass the micro-, meso-, and exosystems; Bronfenbrenner. macula -- The area of the retina that contains the greatest concentration of cones and the fovea centralis. (see picture) macular degeneration -- An age-related condition in which the macula (tissues within the break down, resulting in distorted and blurred vision. magnetic resonance imaging (MRI) -- A magnetic imaging technique by which computers create cross-sectional images of specific body areas or organs; imaging procedures that uses the magnetic resonance of atoms to provide clear images of interior parts of the body. It is particularly useful in diagnosing structural abnormalities of the brain. magnetic resonance spectroscopy (MRS) -- A study that can be done as part of a regular MRI scan. Rather than provide a picture of the brain, it analyzes the presence and amount of certain metabolic components in various brain regions. It is particularly helpful in diagnosing certain inborn errors of metabolism, such as mitochondrial disorders. macule -- a flat, distinct, colored area of the skin that is less than 10 millimeters in diameter and does not include a change in skin texture or thickness. mahatma -- a person to be revered for high-mindedness, wisdom, and selflessness; a person of great prestige in a field of endeavor maieusiophobia -- fear of childbirth maiden archetype -- Jung: represents purity, innocence, and, in all likelihood, naiveté (------------------------------->>) mail-order brides -- Agencies specializing in so-called mail-order brides publish profiles and photos of women mainly for the benefit of American men seeking wives. mainstream -- The educational concept that a child with disabilities should be placed in a general education setting for all or part of the day. This was the government's first attempt at providing a free, appropriate public education for all children in the least restrictive environment. The word was replaced with "inclusion." maintenance stage of learning -- the stage of learning in which the aim is for the mastered skills to remain at the same level of performance as during the proficiency stage. major depression -- a prolonged period of depressed mood major health impairments -- includes blood disorders (e.g., hemophilia, sickle cell anemia), congenital heart defects, chronic renal failure, and type 1 diabetes. Medication can sometimes control the symptoms of these illnesses, and there is generally little impact on development. Another term for "Other Health Impairments." make-believe play -- A type of play in which children pretend, acting out everyday and imaginary activities. According to Vygotsky, this is the ideal social construct for fostering cognitive development in early childhood. malabsorption -- difficulty digesting or absorbing nutrients from food. malabsorption syndrome -- an alteration in the ability of the intestine to absorb nutrients adequately into the bloodstream. It may be due to an abnormality of the gut wall, failure to produce enzymes or bile to aid digestion, or abnormalities in the flora of the gut. Common disorders that can lead to malabsorption syndrome are cystic fibrosis, chronic pancreatitis, celiac disease, short bowel syndrome, intestinal lymphangiectasia, Whipple's disease, inflammatory bowel disease, and irritable bowel syndrome. malaise -- a condition of general bodily weakness or discomfort; often marking the onset of a disease; a vague or unfocused feeling of mental uneasiness; lethargy; discomfort malapropism, malapropped -- the act or habit of misusing words ridiculously, especially by the confusion of words that are similar in sound. Mrs. Malaprop, a character in the 18th century British comedy, The Rivals, by Richard Brinsley Sheridan, constantly confuses words. Malapropisms are named after her. malar hypoplasia -- underdeveloped mid face. malaria -- An infectious, febrile illness caused by a protozoa; transmitted by mosquitoes; tends to become chronic. malaxophobia -- fear of love-play male menopause -- physical changes in men related to age, similar to those that occur in women during menopause. male-pattern baldness -- the most common type of hair loss in men, following a typical pattern of receding hairline and hair thinning on the crown, and is caused by hormones and genetic predisposition (see picture) malevolent -- having or showing a wish to do evil to others malfeasance -- the performance by a public official of an act that is legally unjustified, harmful, or contrary to law; wrongdoing especially of a public trust. malignant; malignancy -- the tendency of a medical condition to become progressively worse and to potentially result in death. malleus -- one of the three small bones in the middle ear that help amplify sound (----------------->) malnourished -- suffering from improper nutrition malnutrition -- prolonged inadequate or excessive intake of nutrients and/or calories required by the body. malocclusion -- A condition in which the upper and lower teeth do not meet properly. (see picture) maltreated children -- those children under age 18 who have been physically, mentally, or sexually abused or neglected by those adults responsible for the child's welfare. mammary glands -- glands in mammal females that produce and secrete milk for the nourishment of the young. mammoplasty -- surgical alteration of the shape of a breast. mana archetypes -- Jung: If you dream about long things, Freud might suggest these things represent the phallus and ultimately sex. But Jung had a very different interpretation. Even dreaming quite specifically about a penis might not have much to do with some unfulfilled need for sex. In primitive societies, phallic symbols do not usually refer to sex at all. They usually symbolize mana, or spiritual power. These symbols would be displayed on occasions when the spirits are being called upon to increase the yield of corn, or fish, or to heal someone. managing stress -- Pauline Boss's alternative to the phrase coping with stress; individual family members' use of their own resources to help their family deal with a stressor or work through a crisis. mandala -- universal symbol combining circle and intersecting lines; Jung: The self, often shown in archetype, is the ultimate unity of personality and is symbolized by the circle, the cross, and the mandala figures that Jung was fond of painting. From the Sanskrit word for "circle", the mandala symbolizes "a safe refuge of inner reconciliation and wholeness." (Jung). Jesus and Buddha are often represented in mandalas, and both achieved perfection on earth. Jung said that perfection can only come in death.--------------------------->>>. mandate -- an authoritative order or command; something that must be done. mandated testing -- testing in public schools that is required at certain grade levels; mandated assessment times are set up by individual states in K -- 12 education. mandated reporters -- those individuals who by law must report suspicions of child abuse to specified agencies; in Tennessee, everyone is considered a mandated reporter of child abuse. mandatory -- something that is required; no choices or alternatives available mandatory arrest laws -- laws that require police to arrest violent intimates when probable cause exists; such laws currently exist in many US states and local jurisdictions. mandatory reporting laws -- laws that require certain classes of professionals to report cases of suspected child or adult abuse, such laws currently exist in all US states. mandible -- lower jaw bone --------------------------------------------------------------------------------> mandibulofacial dystosis -- see Treacher Collins syndrome mandrake roots -- a part of the plant genus Mandragora, belonging to the nightshades family. When a mandrake plant is dug up, the root screams and kills all who hear it. A potion made from mature mandrake roots is curative to a person hurt by the gaze of a basilisk (Harry Potter and the Chamber of Secrets, J.K. Rowling). A group of mandrake roots is a bawl. A mandrake baby is a sapling. mania -- 1) According to sociologist John Alan Lee's theory of the origin of love, one of six basic styles of loving: obsessive love, which consists of strong sexual attraction and emotional intensity, extreme jealousy, and mood swings alternating between ecstasy and despair; 2) a distinct period of abnormally and persistently elevated, expansive, or irritable mood. This mood disturbance is sufficiently severe to cause impairment in function; 3) a personality characteristic of a person who speeds by you on the interstate (maniac). maniaphobia -- fear of insanity manic depression -- see bipolar disorder. Manic depression is a psychiatric disorder consisting of distinct periods of elevated mood and depressed mood. This is a type of psychosis and is associated with disorganization of personality and distortion of reality. manifestation determination -- When disciplining a student who receives special education services, the school must determine whether the student's behavior is a manifestation "caused by" his or her disability. This process must occur when the school proposes to change the student's placement for more than 10 days (according to IDEA 1997; IDEA 2004 has changed this to Special Circumstances: Child may be removed to an Interim Alternative Educational Setting (IAES) for not more than 45 days, without regard to whether or not behavior is a manifestation of the disability, for violations involving weapons, drugs, or infliction of serious bodily injury). manifest content -- Freud: what we usually think of as the dream itself, and what Freudians see as surface, a disguise of the true latent dream material. manifest functions -- according to the structural-functional perspective, functions that are open, stated, and conscious manipulative area -- a place in an early childhood setting for children to enhance their fine motor skills, develop hand-eye coordination, and increase mental, language, and social skills through the use of play materials such as pegboards, puzzles, and games. manipulative materials -- materials that children can handle and work with, such as puzzles, blocks, buttons, and wooden beads. manipulative skills -- are defined as any gross motor skill that usually involves an object being manipulated. More commonly, however, "manipulative" refers to fine motor skills. manipulative tantrums -- tantrums children throw to manipulate others into giving them what they want. manticore -- a sentient creature, capable of human speech. A manticore is very violent, has a human-like head, a lions' body, and the tail of a scorpion. The tail secretes a venom that is instantly fatal to the victim of its sting. A manticore's skin repels virtually all spells and charms, so it is extremely difficult to subdue. The manticore has three rows of gleaming teeth and blood- red eyes. It's shrill sound sounds much like a flute. It is very powerful and can jump great distances. It is a ravenous beast, fond of human flesh. A blast-ended screwt is the result of the mating of a manticore and a fire-crab. Manticores originated in Greece. A group of manticores is a fatality. A manticore baby is a cupcake. manual approach -- involves teaching the use of sign language (ASL) for communication. manual communication -- any formal or established system of hand gestures used for communication, such as fingerspelling or American Sign Language. manual interpreter -- An individual who translates spoken language into sign language (ASL) for people who are deaf. manual prompt -- positioning the teacher's hand around the learner's and putting the learner through the motions required to perform a particular act. manubrium -- the broad, upper part of the sternum. (see picture) maple syrup urine disease -- A disorder of branched chain amino acid metabolism with four identified clinical variants (classic, intermittent, intermediate, and thiamine-responsive); the classic form comprises 75% of cases and is characterized by severe opisthotonos (spasm with body in a bowed position and head and heels bend backward), hypertonia, hypoglycemia, lethargy, and respiratory difficulties. Symptoms appear within the first 48 hours of life; if untreated, it is most often fatal within one month. Untreated survivors have severe intellectual disability and spasticity. The intermittent form presents with periods of ataxia, behavior disturbances, drowsiness, and seizures. Attacks are triggered by infections, excessive protein intake, or other physiological stresses. Individuals with the intermittent form usually demonstrate mild to moderate intellectual disability. Associated complications: acidosis, hypoglycemia, growth retardation, feeding problems, acute episodes that are characterized by muscle fatigue, vomiting, impaired cognitive ability, hyperactivity, sleep disturbance, hallucinations, dystonia, and ataxia. Caused by a deficiency in branched chain alpha-ketoacid dehydrogenase caused by mutations in the genes (at chromosome locations 1p31, 6p22--p21, and 19q13.1-- q13.2) making up this enzyme complex; autosomal recessive. Maple syrup urine disease affects approximately 1 out of every 180,000 newborns in the United States each year. However, in Old Order Mennonites in southeastern Pennsylvania, the disorder affects 1/200 newborns. MAPs -- a process that customizes students' educational programs to their specific visions, strengths, and needs. It is especially effective in planning transitions from school from preschool activities. marasmus -- a disease usually appearing in the first year of life that is caused by a diet low in all essential nutrients. Leads to a wasted condition of the body (------------->). marchen -- the German word for fairy tales. Marfan syndrome -- tall, thin body; upward dislocation of ocular lens; myopia; spider-like limbs; hypermobile joints. Average intelligence expected, although learning disabilities have been reported in up to 50% of children with Marfan syndrome. Associated complications are aortic dilatation or dissection, congestive heart failure, mitral valve prolapse, a caved-in or domed breastbone, flat feet, a high arched palate that causes teeth to be crowded, dislocated lens in the eye, nearsightedness, glaucoma, cataracts, emphysema, sleep apnea, and scoliosis. Caused by a mutation in the fibrillin (FBN-1) gene located on chromosome 15q15--q21.3; autosomal dominant. A cause of deaf-blindness. Marfan syndrome affects 1/20,000 people in North America. See two pictures. marginal -- living within the majority culture but feeling alienated or outcast. marital adjustment -- a measure of marital quality that combines questions that reflect feelings and questions about interaction, communication, and conflicts. marital quality -- marriage success measured in terms of stability, happiness, and flexibility. marital rape -- sexual assault by one's spouse. marital scripts -- expectations a person has about what is appropriate behavior for husbands and wives. marital stability -- refers to whether a married couple stays together; to marriage does not end by separation, divorce, or other means. marital success -- also called marital quality, characteristic of marriage measured in terms of stability, happiness, and flexibility. Maroteaux-Lamy syndrome (MPS VI) -- see mucopolysaccharidoses (MPS) (a cause of deaf blindness) marriage -- an emotional and legal commitment between two people to share emotional and physical intimacy, various tasks, and economic resources. marriage and family enrichment (also called enhancement) -- programs designed to strengthen couples and families. marriage bureaus -- services that arrange introductions for a fee marriage gradient -- see mating gradient marriage sabbatical -- a personal timeout from daily routines for creative, professional, or spiritual growth, for study, reflection, or renewal. marriage squeeze -- a factor that influences dating: one sex has a more limited pool of eligible marriage candidates than the other sex has. married couple household -- a household in which the householder is married and living with his or her spouse. Marshall syndrome -- a very rare genetic disorder (autosomal dominant) that equally affects males and females. It is caused by an abnormality in collagen, a key part of connective tissue. Characteristic facies include an upturned nose, eyes spaced widely apart, and a flat nasal bridge. This gives the person a child-like appearance. The upper part of the skull is abnormally thick, and deposits of calcium may appear in the cranium. There may also be palate abnormalities and early osteoarthritis. Myopia, cataracts, and glaucoma are common; moderate to severe hearing loss preceded by many incidents of otitis media. It is caused by a genetic mutation on COL11A1 (collagen, type XI, alpha 1) on chromosome 1; a cause of deaf-blindness. martyr parenting style -- parenting style in which parents sacrifice everything for their children and exercise little or no authority over them. masculinists -- people who believe that the patriarchal system causes oppression and isolation but who are in favor of males trying to achieve self-realization and self-expression. masculinity -- a gender-linked constellation of personality traits and behavioral patterns traditionally associated with males in a society. masochism -- Freud: caused by an alloy of eroticism and a sadistic superego. It fills the ego with a desire to atone by punishing itself. An original or primary masochism develops into a 1) feminine; 2) erotogenic; or 3) moral masochism via a turning of unresolved sadism against oneself (secondary masochism). Too much internalized death drive and you get masochism; when directed outward, sadism. massed practice -- extra practice of a skill to ensure mastery. mass number -- number of neutrons plus number of protons in an atom. mass spectrometry -- a technique used for identifying chemical, drug, or metabolic abnormalities in the blood or urine. mast cell -- a group of cells called leukocytes. Leucocytes are white blood cells found in plasma with red blood cells (erythrocytes). Mast cells have immunological functions. When they are stimulated, they release chemicals that signal either injury or infection, and cause an inflammation in the area. See white blood cells. mastery -- competency, clear-cut understanding of a complete skill or knowledge. mastery-oriented attributions -- attributions that credit success to high ability and failure to insufficient effort. Lead to high self-esteem and a willingness to approach challenging tasks. mastigophobia -- fear of flogging mastoiditis -- infection of the mastoid air cells that rest in the temporal bone behind the ear. This is an infrequent complication of a chronic middle ear infection (--------------------------------------->). matching -- recognizing the similarities of an attribute of objects. matching hypothesis -- the idea that people seek romantic partners who are similar in level of physical attractiveness. maternal conditions -- infections, diseases, or disorders that occur in a mother during pregnancy, sometimes having the potential to injure the unborn child. maternal deprivation -- process of being denied access to bonding with one's mother. This is a catch-phrase summarizing Bowlby's early work on the effects of separating infants and young children from their mothers. He believed that maternally deprived children were likely to develop asocial or antisocial tendencies, and that juvenile delinquency was mainly a consequence of such separations. The corollary of this was his advocacy of continuous mother-child contact for at least the first five years of life, which earned him the opprobrium of feminists. Subsequent research has confirmed that lack of maternal care does lead o poor social adjustment and relationship difficulties, but suggests that disruption, conflict, and poor maternal handling are more common causes of difficulties later than the loss of the mother in itself. maternal drug use (during pregnancy) -- a cause of deaf blindness. maternal infections -- infections in a mother during pregnancy, sometimes having the potential to injure the unborn child. maternal obesity -- degree of excessive weight in a pregnant woman. maternal Rh incompatibility -- a condition that occurs when a baby with Rh+ blood is born to a mother with Rh- blood. This leads to a breakdown of red blood cells in the baby. maternal serum alpha-fetoprotein -- a prenatal test to detect spina bifida. mathematics learning disabilities -- condition wherein a student's learning disability is most significant in areas related to mathematics. mating gradient -- the tendency of women to marry men who are better educated or more successful than they are. matriarchal -- female-dominated, female-identified, and female-centered. matriarchal family -- family in which the mother holds the power. matriarchal group -- a group in which the mother or eldest female is recognized as the head of the family, kinship group, or tribe. Descent is traced through this woman. matrilineal -- family/kinship system whereby children trace their descent, and perhaps rights and property, through the mother's line. matrilineal society -- a society in which descent, or lineage, is traced through females. matrilocal society -- a society that encourages newly married couples to live with or near the wife's kin, especially her mother's kinship group. maturation -- The biologically controlled process by which each child "unfolds" according to the child's individual timetable. maturational delay -- delay in maturation of the neurological system; a possible cause of learning disabilities. maturationist -- one who believes the human development is a natural unfolding of innate abilities and nearly independent of environmental influence. Maturation theory -- a set of ideas based on the notion that the sequence of behavior and the emergence of personal characteristics develop more through predetermined growth processes that through learning and interaction with the environment; the theory of growth and development proposed and supported by Dr. Arnold Gesell and associates. mature love -- companionate love. mature minor -- a teenage minor who may give consent because the physician judges that he or she understands the nature, purpose, and risks of the proposed treatment; generally limited to minors at least 15 years old where the treatment is for the patient's own benefit and is judged necessary by conservative medical opinion (compare emancipated minor). maxilla -- the bony region of the upper jaw (------------------------------------------------------------------->). maxillary -- pertaining to the upper jaw bone. maxillary hypoplasia -- underdeveloped or incomplete upper jaw mayhap -- perhaps mayhem -- willful and permanent crippling, mutilation, or disfigurement of any part of the body and especially deprivation of a bodily member; needless or willful damage or violence McCune-Albright syndrome (polyostotic fibrous dysplasia) -- large cafe-au-lait spots with irregular borders; fibrous dysplasia of bones (thinning of the bone with replacement of bone marrow with fibrous tissue, producing pain and increasing deformity); bowing of long bones; premature onset of puberty; advanced bone age. Associated complications: hearing or visual impairment, hyperthyroidism, hyperparathyroidism (increased activity of the parathyroid gland, which controls calcium metabolism), abnormal adrenal function, increased risk of malignancy, occasional spinal cord anomalies. Caused by a post mitotic mutation in the GNAS1 gene (causing a defect in the enzyme adenyl cyclase) located on 20q13 chromosome; new mutation arising after fertilization, passed autosomal dominant if reproductive organs are involved; theoretically lethal unless present in the mosaic form. mean -- the average score in a distribution. meaningful curriculum -- chronologically age-appropriate, relevant curriculum provided for each student according to interests, personal goals, and limitations in reaching those goals. meaningful knowledge -- the form of knowing that is learned within the context of what is already known; that knowledge that has meaning because it has particular significance of value to an individual. mean length of utterances (MLU) -- the average length of a child's sentence, which usually increases with age. measles -- a very contagious illness caused by a virus. Symptoms are bloodshot eyes, cough, fever, light sensitivity, muscle pain, rash, runny nose, sore throat, tiny white spots in the mouth. Measles can be prevented by a MMR vaccine. measurement -- quantification of some kind. measurement bias -- an unfairness or inaccuracy of test results that is related to cultural background, sex, or race. measures of central tendency -- measures which are representative of a sample or population. They enable one to be more objective when drawing conclusions or making inferences. These measures identify the center or middle of a set of values and best characterize the distribution. mechanistic model -- orientation based on the belief that it is useful to view human beings in terms of their reactive, machine-like characteristics. mechanophobia -- fear of machinery meconium -- the thick, sticky, greenish-black feces passed by infants during the first day or two after birth ------->. meconium aspiration -- potentially severe illness due to infant inhaling meconium (i.e., feces) into lung passages with first respiratory efforts. Can cause respiration pneumonia and inadequate ventilation for the infant. media -- any material used to create or enhance learning experiences for young children. medial -- toward the center or mid-line. median -- the middlemost score in a distribution. median income -- the income midpoint -- half of a population earns more and half earns less. median nerve -- the nerve that runs through the carpal tunnel of the wrist and connects with the thumb and all fingers of the hand, with the exception of the little finger. Median nerves originate with the cervical spine and are routed through the arm and the forearm. The nerve gathers in compressed form to run through the carpal tunnel and to the fingers. It controls sensation in the hand, and aids in the general nerve function of the upper arm. median plane -- the mid-line plane of the body. It runs vertically and separates the left and right halves of the body. mediastinum -- the area located between the lungs that contains all of the principle tissues and organs of the chest except the lungs. It extends from the sternum back to the vertebral column and is bounded laterally by the pericardium. mediated learning -- Based on the teaching premise that cognitive and social processes are independent factors in all learning. mediation -- a process that is offered without cost to the parents for resolving disagreements for parents about school issues. mediation (divorce) -- a specially trained, neutral person meets with two divorcing people, hears their respective claims, and tries to move them toward a mutual agreement. mediators -- Teacher or other adults who facilitate learning by bridging the gap between the child and the learning environment. mediator (variable) -- another term for intervening variable, that is, a variable that transmits the effects of another. Medicaid -- a government-sponsored health care program for eligible people with disabilities and others that pays for hospital services, laboratory services, and early screening, diagnosis, treatment, and immunization for children. medical family therapy -- a therapeutic framework that uses family systems theory and the biopsychosocial approach in dealing with health problems in family members. medically fragile -- a disability category that includes people who are at risk for medical emergencies and often depend on technological support, such as a ventilator or nutritional supplements, to sustain health or even life. medical model -- model by which human development is viewed according to two dimensions: normal and pathological. Normal refers to the absence of biological problems; pathological refers to alterations in the organism by disease. medical neglect -- a kind of child abuse in which there is failure to provide the medical, dental, or psychiatric care needed to prevent or treat physical or psychological injuries or illness. Medicare -- a government-sponsored national insurance program for people over 65 years of age and eligible people with disabilities. Medicare may pay for hospital and physician-related costs. medicine -- in Native American religions this refers to a mystic power. A medicine bundle, worn on a belt in a pouch, will have various plant pollens and animal parts, such as a tooth or claw, that are thought to impart their sacred power or protection to the wearer. Medicine man -- in Native American societies a healer who is in touch with the spiritual world. A medicine man helps individual as well as the community. Also called a Shaman. meditation -- Jung: a technique of focused introspection. Maslow: one of the aspects of the Fourth Force of Psychology. medium; media -- art materials medium chain fatty acids -- fatty acids that can bypass the normal uptake process and go directly to the liver. medium chain triglycerides (MCT) -- fatty food source that can bypass normal uptake process and go directly to the liver. medley -- a diverse assortment or mixture; hodgepodge; a musical composition made up of a series of songs or short pieces. medulla oblongata -- located in the brain stem, it channels information between the cerebral hemispheres and the spinal cord. It controls respiration, circulation, wakefulness, breathing, and heart rate (see diagram). megadose -- an amount of a vitamin or mineral at least ten times that of RDA. megalophobia -- fear of large objects megavitamin therapies -- see orthomolecular therapy; the use of at least 10 times the required amount of vitamins. meiosis -- reductive cell division occurring only in eggs and sperm in which the daughter cells receive half (23) the number of chromosomes as the parent cells. Makes only 1 viable egg but 4 viable sperms (see diagram----------->). melancholia -- Freud: see depression. For Freud, this shares with mourning a gradual withdrawing of libido from an object known to be lost or dead -- but it is different in that the unconscious hatred felt toward the object with which the ego narcissistically identifies is turned against the ego. One then achieves revenge against the lost object by getting depressed. melanin -- skin pigment. melanocyte -- a pigment producing cell in the skin, hair, and eye that determines their color. The pigment is called melanin. MELAS (Mitochondrial myopathy, Encephalopathy, Lactic acidosis, and Stroke-like episodes) -- One of the mitochondrial disorders; migraine headaches, seizures, stroke-like episodes, encephalopathy (degenerative disease of the brain), myopathy, progressive hearing loss, cortical blindness, ataxia, dementia, lactic acidosis, recurrent vomiting, hemiparesis. Caused by a mutation in mtDNA encoding transfer RNA which causes reduced mitrochondrial protein synthesis; maternal through mtDNA. meld -- merge, blend melissophobia -- fear of bees meme -- an idea, behavior, style, or usage that spreads from person to person within a culture. memory -- mental capacity to store and later recognize or recall previously experienced events. memory and thinking disorders -- one of the common characteristics of children with learning disabilities; deficiency in the use of strategies for memorization; haphazardness in approaches to learning. Poor language skills, which hinder memory; difficulty with short-term auditory and visual memory; and a lack of awareness of skills and strategies needed to solve problems and perform tasks. memory strategies -- deliberate mental activities that improve the likelihood of remembering. menarche -- the onset of the menstrual cycle. mendacious -- given to or characterized by deception or falsehood or divergence from absolute truth. Mendelian traits -- dominant and recessive traits inherited according to the genetic principles put forward by Gregor Mendel. Meniere's disease -- an abnormality of the inner ear that causes vertigo (severe dizziness), tinnitus, fluctuating hearing loss, and the sensation of pressure or pain in the affected ear. It usually only affects one ear and it is a common cause of hearing loss. meningeal -- related to the meninges, the three membranes that surround the brain and spinal cord. meninges -- the three membranes covering the brain and the spinal cord-------------------->>. meningiomas -- tumors of the meninges. They are usually benign. They are more common in women and more common in people between the ages of 40 and 70. Meningiomas may cause seizures, headaches, arm or leg weakness, or vision loss. Also there may sometimes be memory loss, carelessness, and unsteadiness. Meningiomas can be diagnosed by a contrast enhanced CT scan or MRI. meningitis -- infection of the meninges; inflammation of the membranes covering the brain and spinal cord, which can affect vision, hearing, and intelligence; can be viral or bacterial; multifactorial. A cause of deaf-blindness. meningocele -- Similar to myelomeningocele except that the protrusion contains only the covering of the spinal cord and usually causes little or no neurological impairment; contains no nerves or nerve roots. The protective coatings (meninges) come through the open part of the spine like a sac that is pushed out. Cerebrospinal fluid is in the sac and there is usually no nerve damage. Individuals may suffer minor disabilities. New problems can develop later in life. meningoencephalitis -- inflammation of the brain and meninges. meningomyelocele -- see myelomeningocele. Protrusion of meninges and malformed spinal cord through a defect in the vertebral column. Menkes syndrome (kinky hair syndrome) -- An inborn error of copper metabolism presenting at age 1 -- 2 months with "steely" texture of hair and characteristic face with pudgy cheeks. Associated complications: seizures, low body temperature, loose skin, arterial rupture, twisted hair, feeding difficulties, severe intellectual disability, recurrent infections, visual loss, bony abnormalities with tendency toward easy fracture, thrombosis, early death. Caused by a copper deficiency from decreased absorption and/or missing enzymes caused by mutations in the adenosine triphosphatase ATP7A gene at Xq13; X-linked recessive. Patients with Menkes syndrome absorb copper from their diets, but the copper never makes it out of the cells lining the gastrointestinal tract. menopause -- the cessation of ovulation, menstruation, and fertility in women as a result of aging. menophobia -- fear of menstruation mens sana in corpora sano -- a sound mind in a sound body menses -- the menstrual flow in which the endometrial tissue of the uterus is discharged. menstruation -- the discharge from the uterus through the vagina of blood and the unfertilized ova; occurs about every 28 days in non-pregnant woman between puberty and menopause. mental age -- a concept used in psychological assessment that arrives at the general mental ability of a child or youth by matching the tasks the child is able to perform to a scale of typical performance of children of various ages. mental disorders -- psychiatric illnesses or diseases manifested by breakdowns in the adaptational process and expressed primarily as abnormalities of thought, feeling, and behavior, producing either distress or impairment of function. mental representation -- internal depictions of information that the mind can manipulate. mental retardation (MR) -- a disability category of IDEA. Disability characterized by significantly below average intellectual functioning and deficits in adaptive functioning that occur during the developmental period (that is, prior to age 18) that has an adverse effect on education; substantial limitations in functioning, characterized by significantly sub-average intellectual functioning concurrent with related limitations in two or more adaptive skills. Mental retardation manifests prior to age 18. This term has been replaced with the more respectful "intellectual disability." mental rotation -- the ability to imagine how objects would appear if their positions were rotated; the aligning of the self (or an object) to match that of a person or object in a different orientation, all of this mentally. See illustration --------------->>>. mental strategies -- in information processing, procedures that operate on and transform information. mentor -- qualified individual who works with students in areas of interest or ability, guiding the students' development and achievement. merinthophobia -- fear of being bound merit -- in distributive justice (beliefs about how to divide material goods fairly), children in middle years believe that extra rewards should go to someone who has worked especially hard or has performed in an exceptional way. merit pay -- a system for teachers that gives pay bonuses for excellent teaching. merpeople -- beings who live underwater in villages at the bottom of lakes and seas. They speak Mermish, a language that sounds like a horrible screeching noise but which is understandable underwater. They sometimes use lolabugs as weapons. They are also known as sirens, selkies, and merrows. Merpeople can breathe air for short periods of time. They are intelligent and have their own cultural and social structures. They have grayish skin and long, wild, dark green hair. Their eyes are yellow, as are their teeth, and they wear thick ropes of pebbles around their necks. They have powerful silver fish tails that allow them to swim expertly, while their upper body resembles humans. They are very tall. A group of merpeople is a triton. A baby is a merbaby. See picture from Harry Potter and the Goblet of Fire (movie). MERRF (myoclonic epilepsy with ragged red fibers) -- one of the mitochondrial disorders; myoclonic epilepsy, ataxia, spasticity, myopathy, optic atrophy, sensorineural hearing loss, peripheral neuropathy, diabetes, cardiomyopathy, dementia, lipomas (fatty tumors), characteristic ragged red muscle fibers are seen on muscle biopsy examination. Caused by mutations in mtDNA encoding transfer RNA; maternal through mtDNA. me-self -- a sense of self as an object of knowledge and evaluation. Consists of all qualities that make the self unique, including physical characteristics, possessions, attitudes, beliefs, and personality traits. mesencephalon -- midbrain region. mesenchymoma -- tumors composed of cells resembling those of embryonic mesenchyme – unspecialized cells of the embryonic mesoderm – or mesenchyme with its derivatives. meshuggener (muh-SHUG-uhner) -- a foolish or crazy person mesocephalic -- having an intermediate head shape with a width of 76 to 80.0 percent of its length from front to back. mesoderm -- middle cell layer in the embryo. mesosystems -- The relationships between the various environments of the microsystems; Bronfenbrenner. messenger ribonucleic acid (mRNA) -- RNA involved in the translation of genetic information. messianic -- of or relating to the Messiah, his awaited deliverance of the Jews, or the new age of peace expected to follow this; of or relating to Jesus Christ or the salvation believed to have been brought by him; of or relating to any popular leader promising deliverance or an ideal era of peace or prosperity. meta -- transcending ... used with the name of a discipline to designate a new but related discipline designed to deal critically with the original one. meta-analysis -- a comprehensive statistical procedure, whereby research studies are evaluated in an effort to ascertain global statistical patterns, which yield "effect size," reported as standard deviations. metabolic disorders -- The inability to correctly utilize nutrients; disabilities caused by this inability. metabolic syndrome -- a combination of obesity, high blood pressure, diabetes, and high cholesterol. metabolism -- all chemical changes that occur from the time nutrients are absorbed until they are built into body tissue or excreted; the chemical process within living cells by which energy is manufactured so that body systems can carry out their functions. metachromatic leukodystrophy (sulfatide lipidosis) -- one of a group of lysosomal storage disorders in which lysosomes, the cell structures that digest toxic materials, are missing a necessary enzyme; the resulting accumulation of toxins leads to varying degrees of progressive neurological impairment, ranging from unsteady gait to severe rigidity and choreoathetosis. Muscle weakness and ataxia are common. Onset of the infantile form, by age 2 years, usually results in death by age 5. The juvenile form generally begins between 4 and 10 years, is rarer, and progresses more slowly. Two distinct adult onset forms exist, one presenting with neurologica/motor involvement and the other with behavioral abnormalities. Associated complications: seizures, abdominal distension, mental deterioration. Caused by mutations in the arylsulfatase A (ASA) gene on chromosome 22q which cause ASA enzyme deficiency and result in the accumulation of sphingolipid sulfatide; autosomal recessive. metacogniplaying -- coined by Paula Burkhart in 2010, the study of how children think about and engage in play. metacognition -- thinking about thought; awareness of and understanding one's thinking and cognitve processes. metacommunication -- communicating about communicating. metafictional, metafiction -- fiction that discuses, describes, or analyzes a work of fiction or the conventions of fiction metalanguage -- any language or symbolic system used to discuss, describe, or analyze another language or symbolic system. metalinguistic -- the study of the relation between languages and the other cultural systems they refer to. metalinguistic awareness -- the ability to think about language as a system; knowledge about the structure and rules of language. metamessages -- cultural messages about what traits are valued and which differences between people are significant. metamorphmagus -- in the Harry Potter series (J.K. Rowling), a witch or a wizard with the ability to change his or her physical appearance at will, rather than requiring a potion or spell. They are very rare. Nymphadora Tonks and her son Teddy Lupin were metamorphmagi. See picture of Tonks and Remus Lupin, Teddy's parents from Harry Potter movies. metaneeds -- Maslow: people who are self-actualizing need: truth rather than dishonesty; goodness rather than evil; beauty not ugliness or vulgarity; unity, wholeness, and transcendence of opposites, not arbitrariness or forced choices; aliveness not deadness or the mechanization of life; uniqueness not bland uniformity; perfection and necessity, not sloppiness, inconsistency, or accident; completion rather than incompleteness; justice and order, not injustice and lawlessness; simplicity, not unnecessary complexity; richness, not environmental impoverishment; effortlessness, not strain; playfulness, not grim, humorless, drudgery; self-sufficiency, not dependency; and meaningfulness, rather than senselessness. metapathologies -- Maslow: when the metaneeds are not fulfilled, the self-actualizing person responds with depression, despair, disgust, alienation, and a degree of cynicism. metaphase -- the stage in cell division in which each chromosome doubles. metaphor -- comparison of two unalike things using the words "is" or "was". They show how two things that are not alike in most ways are similar in one important way. They are a way to describe something. All the world's a stage, And all the men and women merely players; They all have their exits and their entrances. William Shakespeare, As You Like It metaphysical -- of, or relating to metaphysics; based on speculative or abstract reasoning; highly abstract or theoretical; abstruse; of or relating to the poetry of a group of the 17th century English poets whose verse is characterized by an intellectually challenging style and extended metaphors comparing very dissimilar things. metapsychological -- Freud: taken together, those aspects of Freud's theorizing that are economical (the hydraulics of unpleasure-avoidance through pleasure), dynamic (libido movements among id, ego, and superego), and topographic (psyche as structured into conscious, preconscious, and unconscious layers). Metapsychology also takes clinical observations beyond the consulting room and applies them to everyone, with varying results. Although psychoanalysis began as a treatment method, Freud's real interest was caught by those theorizings that applied it to human psychology in general. Referring to two recent books, Freud wrote this to his friend Oskar Pfister: "I do not know whether you have guessed the hidden link between my "Lay Analysis" and "illusion." In the former I want to protect analysis from physicians, and in the latter from priests. I want to entrust it to a profession that doesn't yet exist, a profession of secular ministers of souls, who don't have to be physicians and must not be priests." metaphyses -- the ends of the shaft of long bones connected to the epiphyses. metastasis -- the spread of a disease from one part of the body to another. When cancer cells metastasize and cause secondary tumors, the cells in the metastatic tumor are like those in the original cancer. meteorophobia -- fear of meteors and meteorites methacillin resistant staphylococcus aureus (MRSA) -- a bacterial infection that is highly resistant to some antibiotics. Staph skin infections cause a red, swollen, and painful area on the skin. Other symptoms are drainage of pus from the site, fever, skin abscess, warmth around the infected area. More serious staph infection symptoms are chest pain, chills, cough, fatigue, fever, malaise, headache, muscle aches, rash, and shortness of breath. It is cause by a strain of the Staphylococcus aureus bacteria. This bacteria normally lives on the skin and sometimes the nasal passages of healthy people. This kind of infection is more common in people who are immuno-compromised, patients in hospitals and long-term care facilities, and those receiving kidney dialysis. methionine -- an amino acid. Methode Clinique -- a kind of information-gathering technique, first used extensively by Jean Piaget, that involves observing children and asking questions as the situation unfolds. The purpose of this technique is to elicit information about how children are thinking as they behave naturally. methylation -- the attachment of methyl groups to DNA at the cytosine base that turns the gene function off. methylmalonic acidemia -- see methylmalonic aciduria methylmalonic aciduria -- In symptomatic cases, this disorder of organic acid metabolism is characterized by repeated episodes of vomiting, lethargy, and coma resulting from acidosis due to a high intake of protein or minor infection. On newborn screening analyses, some individuals with this metabolic abnormality may remain asymptomatic. Associated complications: seizures, neutropenia (decreased white blood cell count), osteoporosis, infections, feeding abnormalities, intellectual disability, and renal failure. Caused by a deficiency of enzyme methylmalonyl-CoA mutase (caused by a mutation in the MUT gene at 6p21); autosomal recessive. See ketotic hyperglycinemia. methylphenidate (Concerta) -- one brand of stimulant medications used for the treatment of ADHD. These medicines increase activity in the frontal lobe of the brain. They improve the ability to absorb and integrate information, improving focus and attention. metonymy -- a figure of speech used in rhetoric in which a thing or concept is not called by its own name but by something intimately associated with that thing or concept. Example: The pen is mightier than the sword. (pen = written word and sword = military force) metopic ridging -- a ridge of bones or suture line on the forehead between the two halves of the frontal bone. The ridging is caused when the two halves close prematurely (----------------------->>>). metric system -- go to this website. It will tell you everything you want to know about the metric system. Plus, it is pretty fascinating! (http://lamar.colostate.edu/~hillger/common.html) metrophobia -- fear of poetry mettle -- vigor and strength of spirit or temperament; staying quality; quality of temperament or disposition; aroused to do one's best mewl -- to cry weakly, whimper M-frame relationship -- a relationship in which both parties have high self-esteem and a strong individual identity but still value the connections they have to each other. microbes -- germs that are so small that they can only be seen through a microscope. microcephaly -- a condition characterized by an abnormally small skull with resulting brain damage and intellectual disability; head circumference more than 2 standard deviations below the average size; multifactorial. A cause of deaf-blindness (see illustration). microcosm -- a little world; especially: the human race or human nature seen as an epitome of the world or the universe; a community or other unity that is an epitome of a larger unity. microculture -- subculture within a larger society that demonstrates some cultural characteristics that differ from the larger society. microcytic anemia -- a failure in the oxygen transport system characterized by abnormally small red blood cells. microdeletion -- a microscopic deletion in a chromosome associated with a contiguous gene syndrome. microdeletion syndromes -- genetic disorders caused by mutations in a small number of contiguous genes, an example being velocardiofacial syndrome. microgenesis -- the development of competence at a single task or activity by a child or adult. microgenetic design -- a research design in which researchers present children with a novel task and follow their mastery over a series of closely spaced sessions. micrognathia -- underdevelopment of the mandible or lower jaw--------------------------------------------->>. microgram -- a metric unit of measurement; one-millionth of a gram. micro-inequities -- subtle forms of discrimination that single out, ignore, or discount women and their contributions simply on the basis of gender. microorganisms -- an animal or plant of microscopic size, especially a bacterium. micropenis -- an unusually small penis microphobia -- fear of small objects microphthalmia -- an abnormally small eyeball. micropremature infant -- an infant born at less than 600 grams (1 pound 5 ounces) or less than 25 weeks gestation; also called micropreemie. microswitch -- a switch, usually used to control a computer, environmental control system, or power wheelchair, that has been adapted so that less pressure than normal is required to activate it. microsystems -- As proposed by Bronfenbrenner, the immediate environments in which a person develops such as a youngster's home and neighborhood. microtia -- small ears (anotia -- no ears) (see top picture, anotia, and below, microtia --->) microtubules -- one of the components of the cytoskeleton. They serve as structural components within cells and are involved in many cellular processes including mitosis, cytokinesis, and vesicular transport. mid-brain -- refers to the geological area behind the frontal lobes, above the brain stem and below the parietal lobes. Structures within it include the thalamus, hippocampus, and amygdala. middle age -- generally speaking, the years between the ages of 35 and 65; from the standpoint of the family development conceptual framework, the middle years of the family life cycle are the launching period for young-adult children and the period before the parents' retirement. middle childhood stage -- time from about age 6 years to 10 years. middle ear -- a small membrane-lined cavity, separated from the outer ear by the eardrum, that transmits sound waves from the eardrum to the partition between the middle ear and the inner ear through a chain of tiny bones. (see illustration over there --->>) middle ear infection -- see otitis media. midfacial hypoplasia -- the upper jaw, cheekbones, and eye sockets have not grown as much as the rest of the face, making the eyes look buggy and an underbite to develop. Also it can be severe enough to cause sleep apnea and snoring. midline -- the imaginary line that divides the body into left and right. midline defects -- disorders that are directly related to the lack of closure of the neural tube; the most common of central nervous system malformations. They are also called dysrhaphic states, and are probably related to both genetic and environmental causes. Examples are anencephaly, spina bifida and all its types, encephalocele, and congenital dermal sinus. midline position -- in the middle or center of the body. midlife crisis -- a period of questioning one's worth, values, and contributions in life, usually beginning in a person's 40s or early 50s. midrange families -- families who are extreme on one dimension of the Couple and Family Map but balanced on the other dimension. There are eight mid-range family types. For example, a family might be structurally enmeshed: extreme on cohesion (enmeshed) but balanced on flexibility (structured). midwife -- a non-physician who attends and facilitates a birth. migraine -- a common type of headache that may occur with symptoms such as nausea, vomiting, and sensitivity to light. milia -- tiny white bumps or small cysts on the skin. Sometimes milia is found on newborns. mild hearing loss -- severity of hearing loss: 15 to 25 dB; difficulty hearing unvoiced consonants (s, p, t, k, th, f, sh); hearing aids are useful. mild mental retardation -- Generally considered to be within an IQ range of 50 to 70; approximately 85% of people who are diagnosed with mental retardation fall into this IQ range. Remember we like the term "intellectual disability" better, right? milestones -- significant developmental events (e.g., first word). milieu strategies -- strategies to facilitate language skills (especially social interaction context) that take advantage of the natural environment (people, materials, activities) to support learning. Milieu strategies include a variety of specific procedures (i.e., time delay, mind-model, incidental teaching). milieu (incidental) teaching -- A strategy in which adults arrange the environment with interesting materials to encourage a child's language development. milksop -- an ineffective, indecisive person Miller-Dieker syndrome -- see lissencephaly syndromes. milligram -- one-thousandth of a gram. milliliter -- one thousandth of a liter; equal to about 15 drops. Mills vs. Board of Education (1972) -- federal court case based on a class-action lawsuit establishing that all children with disabilities in Washington, D.C., are entitled to public education. milquetoast -- a timid, meek, or unassertive person. mindfulness -- term coined by Ellen J. Langer; state of mind characterized by three features: creation of new categories; openness to new information; and awareness of more than one perspective. minding -- a multidimensional concept that describes the need to give ongoing attention to oneself, one's relational partner, and the relationship itself. mindlessness -- term coined by Ellen J. Langer; state of mind characterized by three features: entrapment in old categories; automatic behavior; and acting from a single perspective. minerals -- inorganic chemical elements that are required in the diet to support growth and repair tissue and to regulate body functions. minilaparotomy -- type of laparotomy that leaves a smaller scar. minimal brain dysfunction -- a once popular term used to describe the learning disability of children with no actual evidence of brain damage. minimal distance principle (MDP) -- the assumption that the noun most closely preceding the verb is the subject of the sentence. miniscule -- written in or in the size or style of lowercase letters; very small. minion -- a servile follower or subordinate of a person in power; a favored or highly regarded person; a minor official; dainty; elegant; trim; pretty. See minion from Despicable Me. minority group -- a social group that differs from the rest of the population in some ways and that often experiences discrimination and prejudices. minotaur -- a monster, the offspring of Pasiphae and the Cretan bull, that has the head of a bull on the body of a man. Housed in the Cretan Labyrinth, it was fed on human flesh until Theseus, helped by Ariadne, killed it. By then, of course, it had mated so that the species lives on, much to the terror of people everywhere. Dante also talks of a minotaur, chief among those damned for their violent natures, men of blood. The minotaur rises, enraged and distracted. Minotaurs are friends with centaurs. A group of minotaurs is a meanness. A minotaur baby is a minitaur. mirror writing -- writing backwards from right to left, making letters that look like ordinary writing seen in a mirror. misanthropist -- a generalized dislike, distrust, disgust, contempt, and hatred of the human species, human nature, or society. misarticulation -- improper pronunciation of words and word sounds. misbehavior -- improper behavior or conduct. miscarriage -- the termination of a pregnancy from natural causes before the fetus is viable outside the mother (during the first or second trimester of pregnancy); also called spontaneous abortion. misconstrue -- to understand or explain wrongly; misinterpret miseducation -- David Elkind's term describing the end result of contemporary parents rushing their children into formal education too early. misogynist -- hatred, dislike, or mistrust of women. misophobia, mysophobia, molysmophobia, molysomophobia -- fear of contamination missense mutation -- a point mutation in which a single nucleotide is changed, resulting in a codon that codes for a different amino acid. This can render the resulting protein nonfunctional. Missense mutations result in such disorders as sickle cell anemia, amyotrophic lateral sclerosis, and Marfan syndrome. mitochondria -- a membrane-enclosed organelle found in most eukaryotic cells. They generate most of the cell's energy. mitochondrial disorders (mitochondrial encephalopathies and myopathies) -- This diverse group of disorders is linked by a common etiology: abnormal function of the mitochondria (energy-producing intracellular structures) or mitochondrial metabolism. Mitochondrial disorders can affect every organ system. Common features include ptosis, external ophthalmoplegia (paralysis of the external eye muscles), myopathy, cardiomyopathy, short stature, and hypoparathyroidism. Associated complications: seizures, sensorineural hearing loss, optic atrophy, retinitis pigmentosa (pigmentary changes in the retina causing loss of peripheral vision and clumping of pigment), cataracts, diabetes, migraine, intestinal pseudo-obstruction, reflux, renal problems, exercise intolerance. Cause: genes encoding nuclear DNA and mitochondrial DNA (mtDNA) are known to cause mitochondrial disorders. Mutations in different genes may cause the same symptoms. Inheritance is autosomal recessive, autosomal dominant, new mutation, or may be inherited through the mother through mtDNA. Mitochondrial disorders include Kearns-Sayre syndrome, Leber hereditary optic neuropathy (Leber's congenital amaurosis, LHON), Leigh Syndrome (subacute necrotizing encephalomyopathy), MELAS, MERRF, NARP. Can cause deaf-blindness. Abnormalities of mitochondrial DNA can produce either an isolated hearing loss, or a hearing loss associated with other features of mitochondrial disorders. Sensorineural hearing loss. mitochondrial myopathy -- congenital muscle disorder caused by a mutation in the mitochondrial DNA. mitosis -- cell division in which two daughter cells of identical chromosomal composition to the parent cell are formed; each contains 46 chromosomes (see diagram above, beside meiosis). mitral valve -- valve between the left atrium and the left ventricle; permits the left ventricle to contract and pump blood out of the aorta without regurgitation of blood back into the left atrium; a mitral valve prolapse occurs when this valve does not close properly. Symptoms of mitral valve prolapse are palpitations, chest pain, difficulty breathing, fatigue, cough, and shortness of breath-->. mitral valve prolapse -- a heart problem in which the valve that separates the left upper and lower chambers of the heart does not close properly. See above for symptoms. mixed ability grouping structure -- arrangement of students into groups whose members are performing at various levels on the skills targeted for instruction. mixed age groups -- also known as heterogeneous, multi-age, vertical, ungraded, non-graded, and family grouping; groups of children not separated by chronological age. mixed cerebral palsy -- type of cerebral palsy that includes characteristics of spastic, athetoid, dyskinetic, ataxic cerebral palsy. mixed hearing loss -- a hearing loss resulting from an abnormal sense organ (inner ear) and/or a damaged auditory nerve (sensorineural hearing loss) as well as a conductive hearing loss (damage or blockage in the outer ear or middle ear). mixed message -- a message in which there is a discrepancy between the verbal and nonverbal components. The receiver hears one thing but simultaneously feels something else. mixed methods research -- this is a type of study in which family researchers use both qualitative and quantitative research techniques, thus benefiting from the strengths of both approaches to research. MLU -- see mean length of utterances. MMR vaccination -- a vaccine that protects against measles, mumps, and rubella, all of which are potentially serious diseases of childhood. The first MMR vaccine should be given when the child is between 12 and 15 months old. A second MMR vaccine is recommended before starting school, about 4 to 6 years. Adults who are 18 and older and were born after 1956 should receive a vaccine if they only had one MMR prior to school entry. Those who were born during or before 1956 are believed to be immune. mnemonics -- making up a rhyme, melody, or saying to aid in learning information, making it easier to recall (i.e., colors of the rainbow -- ROY G. BIV). See letter strategies. mobiles -- An art form made up of balanced lengths of wire or string to which bits of various materials are attached so that air current move them about when they are hung up. mobility -- The ability to move safely and efficiently from one point to another; the process of using one's senses to determine their position in relation to other objects in the environment. mobility devices -- objects, such as a long white cane or adapted cane devices, which serve as an "extension" of the user's arms, hands, and fingers, and provide protection from obstacles while allowing access to needed information about the environment. modalities of knowledge acquisition -- these are divided into four basic groups: visual, auditory, tactile, and kinesthetic. mode -- the most common score in a distribution. modeling -- An instructional technique by which one person demonstrates how to do a task or solve a problem; (three-dimensional) manipulating and shaping flexible materials. modeling behavior -- a characteristic of dramatic play in which children imitate what they have observed. model program -- a program that implements and evaluates new procedures or techniques to serve as a basis for the development of other programs. mode of representation -- in Bruner's theory, one of three ways in which knowledge can be represented. moderate hearing loss -- severity of hearing loss: 30 to 50 dB; can usually hear conversational level speech as a whisper or just detect some sound when people speak. Hearing aids are essential if the loss is permanent. moderate mental retardation -- generally believed to be an IQ range between 35 to 50. Of the people who are diagnosed with mental retardation, only 10% fall into this category. Gross and fine motor coordination is usually delayed. However, the individual is often ambulatory and capable of independent mobility. Perceptual motor skills exist (e.g., body awareness, sense of touch, eye-hand coordination) but are often delayed in comparison to the norm. Most individuals who are moderately mentally retarded have delays or deviations in speech and language skills, but many develop language abilities that make possible some level of communication with others. ("Intellectual disability" is more respectful.) (remember) moderator (variable) -- a variable that influences (moderates) the relation between 2 other variables and thus produces an interaction effect. modern family -- see nuclear family. modification -- a change in assessment procedures that DOES alter what the assessment measures and the comparability of results; adjustments to assignments or tests that reduce the requirements. modifier genes -- genes that can enhance or dilute the effects of other genes. modulation of dependency -- the state of a parent-child relationship in late adolescence or early adulthood in which a child's increasing independence (autonomy) balances his or her continuing emotional attachment to his or her parents. Moebius sequence (congenital facial diplegia) -- expressionless face and facial weakness (bilateral in 92% of cases and unilateral in 8%) due to palsies of the 6th, 7th, and occasionally the 12th cranial nerves; occasional abnormalities of fingers and legs; micrognathia, eye abnormalities including esotropia (crossed eyes) and vision problems including myopia, astigmatism, and amblyopia; craniofacial malformations; feeding difficulties, oral motor dysfunction, articulation disorder, occasional tracheal or laryngeal anomalies, gross and fine motor delay and dysfunction. Intellectual disability in 10% to 50%. Cause: linked to chromosome 13q12 - q13 and 1p34; mostly sporadic, possibly due to a new mutation; rare reports of autosomal dominant, autosomal recessive, and X-linked cases. A cause of deaf-blindness. moil -- to work hard; drudge; to be in continuous agitation; churn; swirl moksha -- in Hinduism a state of perfection in which the soul resides after liberation from the cycle of rebirths. The more familiar term is the Buddhist Nirvana. mold -- a fuzzy growth produced by fungi. molding -- the pressing together, or even overlapping of the bones of the baby's skull, to accommodate passage of the baby through the birth canal. -------------------------------->>> molecule -- the smallest particle of a substance that retains the chemical and physical properties of the substance and is composed of two or more atoms; a group of like or different atoms held together by chemical forces. mollycoddling -- to be overprotective and indulgent towards monilial -- pertaining to, or caused by a fungus of the genus Candida (Monilia). Monilia is a yeastlike imperfect fungi that is normally present on the skin, and in the mucous membranes of the mouth, intestinal tract, and vagina. It may become pathogenic, especially C. albicans, the causative agent of thrush. monocytes -- a type of white blood cell that plays a role in the immune system function. They make up between 1% and 3% of the total white cells in the body. They are made in the bone marrow. monogamy -- a relationship in which a man or woman has only one mate. monologue -- when children speak out loud to themselves; see collective monologue. mononucleosis -- a viral illness whose symptoms include fever, malaise, sore throat, swollen lymph nodes, and an enlarged spleen. monophobia -- fear of solitude monoplegia -- type of paralysis that only involves one limb. monosomy -- chromosome disorder in which one chromosome is absent. The most common example is Turner syndrome, XO. monosomy X -- see Turner syndrome. monotropy -- an ethological term introduced by Bowlby to denote the exclusive attachment of a child to its principal care-giver, usually the mother. He was impressed by Lorenz's studies of geese and their young which suggested that the goslings became imprinted onto a moving object at a sensitive period in the first day or two of life. Bowlby thought that a similar process occurred in humans. In fact, imprinting seems not to be a feature of primate development, where attachments develop gradually and over a wide range from the early months to adolescence. Also, attachment in humans is not so much monotropic as hierarchical, with a list of preferred care-givers, with parents at the top, but closely followed by grandparents, siblings, aunts, and so on. monounsaturated fatty acid (MUFA) -- a fatty acid that has only one bond in its structure, and that is not fully saturated with hydrogen. monozygotic twins (identical twins) -- twins who share the same genetic code because they both developed from only one fertilized egg, which divided into two separate individuals (-->>). montane -- pertaining to, growing in, or inhabiting mountainous regions; the lower vegetation belt on mountains. mood disorders -- prolonged or severe depression or mania (elation) or swings between these extremes. mood stabilizers -- a psychiatric medication used to treat mood disorders characterized by intense and sustained mood shifts. The most common is bipolar disorder, where mood stabilizers suppress swings between mania and depression. These drugs are also used in borderline personality disorder. Most mood stabilizers are anticonvulsants, with the exception of lithium. moral character -- According to Darcia Navarez, the fourth moral component of moral education. Having the strength of one's own convictions; controlling impulses and steadfastly behaving in accordance with one's own moral values. moral development -- a theory put forth by Lawrence Kohlberg. moral domain -- issues that concern universal principles reflecting concepts of harm, welfare, and fairness. moralistic period of childrearing -- the dominant cultural view of childhood from the sixteenth through the eighteenth century, childhood was viewed as a period during which children must be disciplined and prepared for adulthood. morality -- characteristic of making choices based on a set of standards set by a social group. The capacity to distinguish right from wrong, and to accommodate the needs of others. In young children, morality is externally controlled by adults; eventually it will become internally controlled. moral judgment -- According to Darcia Navarez, the second moral component of moral education. Reasoning about right and wrong, evaluating possible courses of action to determine which is just and fair. moral motivation -- According to Darcia Navarez, the third moral component of moral education. Granting moral values a high priority, evaluating moral values above personal values. moral realism -- the belief that morality is based on conforming to established rules set by powerful adults. moral sensitivity -- According to Daria Navarez, the first moral component of moral education. Moral sensitivity means interpreting the situation, using cause and effect reasoning and perspective taking to predict how one's actions are likely to affect others. moratorium -- identity status of those adolescents who are actively exploring identity issues but have not yet made any firm commitment. morbidity -- medical complication of an illness, procedure, or operation. morning sickness -- nausea experienced by many women during the first trimester of pregnancy, often but not exclusively in the morning. moro reflex -- primitive reflex present in the newborn in which the infant throws the arms out in an 'embrace' attitude. This reflex disappears by age 6 months. (see illustration) morphemes -- smallest unit of language morphogenic system -- a system that is open to growth and change; also called an open system. morphological development -- evolution of word structure and word parts. morphological inflections -- bound morphemes or small word units that change the meaning of words (e.g., 's, -ed, pre-, etc.) morphology -- the meaning units in words. morphostatic system -- a system that has the capacity to maintain the status quo, thus avoiding a change; also called closed system. Morquio syndrome (MPS IV) -- see mucupolysaccharidoses (MPS); a cause of deaf-blindness. mortality -- the death rate; the ratio of total number of deaths to the total number in the population. morula -- the group of cells formed by the first divisions of a fertilized egg. Mosaic Down syndrome -- Down syndrome that occurs as the result of mosaicism. Some cells in the body (for a child with Down Syndrome) have 3 (instead of the normal 2) chromosome 21, the usual chromosomal definition of Down syndrome or Trisomy 21. With mosaicism, some cells in the child's body have the extra 21st and some don't. So far, Down syndrome and mosaic Down syndrome seem to have the same characteristics. Sporadic or new mutation; see the precious blond child. mosaicism -- the presence of two genetically distinct types of cells in one individual -- for example, a child with Down syndrome who has some cells containing 46 chromosomes and some cells containing 47 chromosomes. Moses -- Freud: based on work by Sellin, Frazier, and others, Freud speculated two Moses: an Egyptian nobleman who lived near the time of the Egyptian pharaoh Akhenaton, the founder of the first monotheism, and gave the Hebrews a modified version of that religion and was killed by them as a result; and a Midianite who resurrected this religion, modified it still further, and coupled it with the Egyptian rite of circumcision, thereby setting the Hebrews apart as a chosen people. MOSF -- see multi-organ system failure. mother archetype -- Jung: symbolized by the primordial mother or "earth mother" of mythology, by Eve and Mary in western traditions, and by less personal symbols such as the church, the nation, a forest, or the ocean. According to Jung, someone whose mother failed to satisfy the demands of the archetype may well be one that spends his or her life seeking comfort in the church, or in identification with "the motherland," or in meditating upon the figure of Mary, or a life at sea. (---------------------->) motherese (fatherese) -- unique infant-directed speech patterns that adults use with babies; also called child directed speech. motif -- in literature, a simple story element out of which an entire narrative may be woven, such as a princess being abducted by a dragon or sorcerer. In folklore, a motif is a recurrent story element such as an incident, character, or theme. Folkloric motifs recur in diverse stories from many different cultures (e.g., identifying the true hero or heroine by a specific sign or test such as Cinderella's slipper test). motif index -- developed by the American folklorist Stith Thompson, this multi-volume index leads readers to stories in collections where specific motifs can be found. motility -- the ability to move spontaneously and actively, consuming energy in the process. motility disorder -- abnormal intestinal contractions, such as spasms and intestinal paralysis, that can result in the inability to eat, severe abdominal pain, nausea, vomiting, maldigestion, weight loss, diarrhea, constipation, and incontinence. Some motility disorders are gastroparesis, achalasia, gastroesophageal reflux disease, chronic intestinal pseudoobstruction, irritable bowel syndrome, and others. motor aphasia -- see expressive aphasia or Broca's aphasia motor cortex -- the region of the cerebral cortex in the brain which influences movements of the face, neck, trunk, arm, and leg. motor delays -- areas of disabilities that involve skeletal and muscle movement. motor development -- The development of the ability to move freely, including coordination, balance, and small motor motions. motor neuron diseases -- a group of progressive neurological disorders that destroy cells that control essential muscle activity such as speaking, walking, breathing, and swallowing. Normally messages from nerve cells in the brain are transmitted to nerve cells in the brain stem and spinal cord and then to particular muscles. If there are disruptions in these signals, the result can be gradual muscle weakening, wasting away, and uncontrollable twitching (fasciculations). Eventually the ability to control voluntary movement can be lost. Some motor neuron diseases are amyotrophic lateral sclerosis, progressive bulbar palsy, primary lateral sclerosis, progressive muscular atrophy, spinal muscular atrophy, and post-polio syndrome. motor neuropathy -- see peripheral neuropathy motorphobia -- fear of automobiles motor planning difficulties -- lack of ability to plan and carry out movements, frequently resulting in awkward or uncoordinated movements. motor point block -- the injection of a denaturing agent into the nerve supply of a spastic muscle. motor rigidity/ spasticity -- increased resistance to stretch; associated with weakness, increased deep reflexes, and diminished superficial reflexes; marked by gross movements that are uncoordinated or impossible mottling -- marked with spots of dense white or brown coloring. mouth twitching -- a common tic, when it is purposeless or obsessive. Others examples are shoulder shrugging or throat clearing. movement and music area -- An activity area in which there is room for dancing, running, climbing, jumping, skipping . . . and singing, listening to music, or making music. movement disorder -- a group of diseases that affect the ability to produce and control body movement. Some movement disorders are ataxia, cerebral palsy, Huntington's disease, Parkinson's disease, Tourette syndrome, and Wilson's disease. movement education -- a success-oriented, child-centered form of physical education emphasizing fundamental movements and the discovery of their variations, which can later be used in games, sports, dance, gymnastics, and life itself. movement therapy -- exercise therapy under the direct care of a physical therapist. Mowat sensor -- a hand-held travel aid, approximately the size of a flashlight, used by people who are blind. It serves as an alternate to a cane for finding obstacles in the person's pathway. MPS 1 (Hurler syndrome, Scheie syndrome, Hurler-Scheie syndrome) -- due to the wide spectrum of clinical variability seen in patients with MPS1, patients with the mild form were originally thought to have a distinct disorder separate from those with severe symptoms. The mild condition was called Scheie syndrome (also called MPS V), and the severe form of the disorder was previously called Hurler syndrome. Determination of a common enzyme deficiency in both conditions represented the variable presentation of a single disease. They are now noted as IH and IS. Patients with the severe form of the disease have short stature, gradual coarsening of facial features in early childhood, including hypertrichosis (excessive hair), large skull, organomegaly, prominent lips, corneal clouding, dysostosis (malformed bones), stiffening of joints. There is progressive intellectual deterioration and spasticity. The milder form is characterized by typical stature, typical intelligence, and survival into adulthood. Associated complications: chronic ear infections, hearing loss, occasional hernia and cardiac valve changes, visual impairments, brain cysts, airway obstruction. Caused by a deficiency of enzyme alpha-L-iduronidase caused by mutations in the iduronidase gene on chromosome 4p16.3; autosomal recessive. MPS II (Hunter syndrome) -- Type IIA is severe; type IIB is mild. Features include short stature, enlarged liver and spleen, coarsening of facial features with hypertrichosis beginning in early childhood, presence of pebbly ivory colored skin lesion on the back, upper arms, and thighs. Mild to absent intellectual disability in type IIB; this subtype is compatible with survival to adulthood. Type IIA is highlighted by progressive intellectual deterioration first noted between 2 and 3 years of age; death occurs before age 15 in most cases and is similar to MPS IH, but with clear corneas. Associated complications are sensorineural hearing loss; retinitis pigmentosa with visual loss; macrocephaly; stiffening of joints, particularly those in the hands; cardiac valve disease in 90%; hernia; respiratory insufficiency; chronic diarrhea in 65%; seizures in 66%. Caused by a deficiency of the enzyme iduronate 2-sulfatase caused by mutations in this gene on chromosome Xq28; X-linked recessive. MPS III (Sanfilipo syndrome) -- Four distinct types representing four different enzyme defects with similar clinical features; clinical features present between 2 and 6 years in children who otherwise appear normal. There is mild coarsening of facial features, coarse hair and hirsutism, absence of corneal clouding, mild enlargement of the liver, joint stiffness, sleep disorders, and progressive mental deterioration. Deterioration is most rapid in type IIIA; death occurs by 10 -- 20 years in most cases. Associated complications: severe behavioral disturbances by age 4 to 6 years, dysostosis, diarrhea in 50%, progressive spasticity and ataxia, precocious puberty, central breathing problems with advancing disease. Cause: Type IIIA: Deficiency of enzyme heparane sulfatase caused by mutations in sulfamidase gene on 17q25.3. Type IIIB: deficiency of enzyme alpha-N-acetylglucosaminidase caused by mutations in the NAGLU gene on 17q21. Type IIIC: deficiency of enzyme acetyl-CoA: alpha-glucosaminide N-acetyltransferase caused by mutations in a gene linked to chromosome 14. Type IIID: deficiency of enzyme N-acetyl-alpha-glucosaminine-6-sulfatase caused by mutations in the G6S gene linked to chromosome 12q14; autosomal recessive. MR -- see mental retardation MRI -- see magnetic resonance imaging. mRNA -- see messenger ribonucleic acid. MRS -- see magnetic resonance spectroscopy. MSUD -- see maple syrup urine disease mtDNA -- mitochondrial DNA -- structures within cells that convert the energy from food into a form that the cells can used. Mitochondrial DNA have a small amount of their own DNA (different than the DNA packaged in chromosomes in the cell nucleus.) This DNA is known as mitochondrial DNA or mtDNA. Mitochondrial DNA contains 37 genes, all essential for normal mitochondrial function. Thirteen provide instructions for making enzymes to use oxygen and simple sugars to make adenosine triphosphate (the cell's main energy source). The remaining provide instructions for making molecules called transfer RNA (tRNA) and ribosomal RNA (rRNA) which are chemical cousins of DNA. tRNA and rRNA help assemble amino acids into functioning proteins. whew! mucopolysaccharidoses (MPS) -- a group of lysosomal storage disorders (for description see metachromatic leukodystrophy) in which glycosaminoglycans accumulate within the lysosomes; there are seven distinguishable forms of the disorder, each with two or more subgroups. Features shared by most include coarse facial features, thick skin, hirsutism, corneal clouding, organomegaly (enlargement of the spleen and liver), growth deficiency, intellectual disability, cardiomyopathy, and skeletal dysplasia are also seen. All are autosomal recessive except for MPSII, Hunter syndrome. Mucopolysaccharidoses (MPS) disorders include MPS I (Hurler syndrome, Scheie syndrome, Hurler-Scheie syndrome), MPS II (Hunter syndrome), MPS III (Sanfilioppo syndrome). mucosal -- pertaining to the mucus membrane lining organs, such as the mouth, stomach, and vagina. mucous membranes -- a membrane lining all body passages that communicate with the air, such as the respiratory and alimentary tracts, and having cells and associated glands that secrete mucus. Also called mucosa. mucus -- a slippery secretion produced by, and covering, mucous membranes. muggles -- in the Harry Potter series (J.K. Rowling), non-magical humans who were not born into the magical world. See picture of Dudley Dursley, Harry's muggle cousin, from the movie, Harry Potter and the Order of the Phoenix. multicultural education -- education that promotes learning about multiple cultures and their values. multicultural factors in transition -- concerns that must be addressed in transition planning when the family making the transition is from a culture other than the dominant one in the agency. multidimensional -- The relationship among the many factors that comprise a learning sequence. multidimensional model of intelligence -- considers multiple domains of intelligence as contrasted to concentrating only on intellectual ability or academic achievement. multidisciplinary -- A team approach in which the professionals provide isolated assessment and intervention services that are often fragmented and confusing to families; professional team in which assessment, IEP development and design, and implementations of instruction, therapy, and evaluation are completed individually by each professional. multidisciplinary assessment -- type of assessment in which specialists from several disciplines assess and evaluate a child independently and submit separate reports. multidisciplinary team -- a team in which professionals act as consultants but do not provide hands-on treatment. multifactored evaluation (MFE) -- an assessment of a student's abilities that combines several sources of data. multifactorial -- describing an inheritance pattern in which environment and heredity interact. multigenerational household -- a household that consists of the householder and his or her children and grandchildren. Or a householder and his or her parents and children. Or a householder and his or her parents and grandchildren. Or any way that it can be made to consist of more than 2 generations. multilevel instruction -- differing levels of instruction that provide students with many different ways to access and learn content within the general education curriculum. multilingual -- degrees of fluency or literacy in several languages (in an individual or a community). multimedia artwork -- an art form and contemporary art movement which emphasizes the integration of all art forms. multimodal treatments -- involves multiple interventions or treatments across modes or types of therapies. Multimodal Treatment Study of Children with ADHD (MTA) -- large-scale, federally funded research project that explored the effectiveness of various interventions for children with ADHD. multi-organ system failure (MOSF) -- results from the diving reflex during severe hypoxic encephalopathy (HIE). multiparous women -- women who have previously given birth (and who are pregnant for a 2nd or more time). multiple acyl-CoA dehydrogenase deficiency -- see glutaric acidemia, type II. multiple carboxylase deficiency, infantile or early form (holocarboxylase synthetase deficiency) -- disorder of organic acid metabolism characterized by seizures, hypotonia, lethargy, coma, skin rash, alopecia (loss of hair from skin areas where it is normally present), and acidosis. Often, the presenting feature is feeding difficulty or respiratory distress. Associated complications: intellectual disability, hearing impairment, optic atrophy with visual impairment, recurrent infections, vomiting. Caused by mutation causing enzyme deficiencies of holocarboxylase synthetase, or 3-methylcrotonyl-CoA carboxylase; autosomal recessive. multiple carboxylase deficiency, late onset, juvenile form (biotinidase deficiency) -- a disorder characterized by varying degrees of intellectual disability, hypotonia, seizures (often infantile spasms), alopecia, skin rash, delayed myelination and lactic acidosis; the onset of symptoms usually occur between 2 weeks and 2 years of age. Associated complications: hearing and visual impairment; respiratory difficulties and apnea, recurrent infections. Caused by defects in various enzymes for biotin transport or metabolism; genetic mutations have been identified in the biotinidase gene on chromosome 3p25 and the holocarboxylase synthetase gene on chromosome 21q22.1; autosomal recessive. multiple disabilities -- A disability category of IDEA; having more than one disabling condition. Concomitant impairments (such as intellectual disability-blindness, intellectual disability-orthopedic impairment, etc.), the combination of which causes such severe educational needs that the individual cannot be accommodated in special education programs designed solely for one of the impairments. The term does not include deaf-blindness. multiple intelligences -- individual ways of processing information; the theory that people have intelligence across several domains, including linguistic, logical-mathematical, spatial, musical, bodily-kinesthetic, interpersonal, intrapersonal, existential, and naturalist. This theory was developed by Howard Gardner. multiple means of engagement -- involving students in activities by using a variety of modes of representation and expression to address their interests. multiple means of expression -- encouraging students to respond in different ways, in accordance with their strengths. multiple means of representation -- presenting information in various formats to reduce or avoid sensory and cognitive barriers to learning. multiple sclerosis -- a nervous system disease that affects the brain and spinal cord. It damages the myelin sheath, the material that surrounds and protects nerve cells. Symptoms of multiple sclerosis are visual disturbances, muscle weakness, trouble with coordination and balance, sensations such as numbness or prickling (pins and needles), and memory problems. Cause is unknown. It affects more women than men. multiple system levels -- general systems theory holds that systems are embedded within one's other systems, layer upon layer. multiply disabled -- An IDEA term for having more than one disabling condition; a category in IDEA. multiracial relationship -- relationships in which people from different racial backgrounds are romantically involved. multisyllable word recognition -- recognition of words that have two or more syllables. mummy -- the preserved remains of an animal or human body, from which fluids have been removed. In ancient Egypt, humans and cats were mummified as a necessary step in preparing the deceased for the afterlife. A mummy is sometimes animated by a dark wizard (similar to the inferius). If reanimated, a mummy is a frightening creature, bandaged, bloody, and sightless. A group of mummies is a pyramid. A mummy baby is an infant. mumps -- a contagious disease that leads to painful swelling of the salivary glands, which produce saliva. Saliva moistens food and helps with chewing and swallowing. Symptoms are face pain, fever, headache, sore throat, swelling of the glands between the ear and the jaw, swelling of the temples or jaw. Mumps are caused by a virus. The MMR vaccine against measles, mumps, and rubella protects against mumps. Munchausen by proxy -- a constellation of behaviors whereby an adult uses her child as the vehicle for fabricated illness. mural -- a story-telling picture or panel intended for a large wall space. muscles -- masses of tough, elastic tissue that pull our bones when we move. Together, bones, muscles, and joints -- along with tendons, ligaments, and cartilage -- form the musculoskeletal system. The human body has more than 650 muscles, which make up half of a person's weight. They are connected to bones by tough, cord-like tissues called tendons, which allow muscles to pull on bones. There are three different kinds of muscles: skeletal (or voluntary), smooth (or involuntary), and cardiac. muscle spindles -- muscle fibers that are part of the reflex arc that controls muscular contraction. muscle tone -- either a tense or relaxed state that affects the ability to flex or extend a muscle smoothly. muscular dystrophy -- a group of inherited, chronic disorders that are characterized by gradual wasting and weakening of the voluntary skeletal muscles. muscular dystrophy, Duchenne (DMD) and Becker (BMD) types -- progressive proximal muscular degeneration, muscle wasting, hypertrophy (enlargement) of calves, cardiomyopathy, onset of symptoms in DMD occurs before 3 years. Loss of ability to walk independently occurs by adolescence in DMD. The onset in BMD is later, and the progression slower. Associated complications: congestive heart failure, scoliosis, flexion contractures, respiratory compromise, and intestinal motility dysfunction (causing constipation); approximately 1/3 of boys with DMD have learning disabilities or intellectual disability. Cause: mutations in the gene that encodes dystrophin localized in Xp21.1; X-linked recessive, with 1/3 of cases due to a new mutation. musculoskeletal -- referring to the muscle and bone support systems of the body. musculoskeletal disorders -- physical disabilities that are the result of problems related to the skeleton or muscles. musical/rhythmic learner -- in Gardner's theory, this learner is oriented toward music, rhythmic sounds, and environmental sounds. Often called the "music lover." Musical intelligence is the ability to appreciate and produce pitch, rhythm, and aesthetic quality to the forms of musical expression. music center -- a place for listening to records, tapes, singing, creating dance, and playing musical instruments (in an early childhood setting). musicophobia, melophobia -- fear of music music therapist -- Individual trained in an approved music therapy program who uses music to enhance development. musophobia, muriphobia -- fear of mice mutation -- a change in a gene that occurs by chance, serendipitously, if you will. mutism -- the inability to speak. mutual dependency -- the sharing of pleasures, ideas, jokes, and sexual desires mutual exclusivity bias -- in the early phase of vocabulary growth, children's assumption that words refer to entirely separate (non-overlapping) categories. mutual gaze -- The steady looking at one another's face that goes on between healthy newborns and their parent or primary caregiver. mutual goal -- shared goal that is the basis for collaboration; should clearly be stated to achieve collaboration. mutual mothering -- a mother-daughter relationship characterized by a mutual propensity for mothers and daughters to supervise each other's lives. myasthenia gravis -- the most common symptoms are fatigability after repetitive movements and fluctuation of the symptoms throughout the day. Caused by an impairment in formation, binding, or use of acetylcholine at the neuromuscular junction. Although in rare cases, genetic in origin, it is most often acquired as an autoimmune disorder. mycobacteria -- bacteria that cause tuberculosis (a chronic gramulomatous disease) and leprosy. myctophobia -- fear of darkness myelin -- tissue that covers the nerves to enhance conductivity of nerve impulses myelination -- the forming of the myelin sheath, the material in the membrane of certain cells in the brain; the development of the myelination of the brain seems to parallel Piagetian stages of cognitive development. The myelin sheath improves the efficiency of message transfer between the brain cells. myelin sheath -- the insulating envelope of myelin that surrounds the core of a nerve fiber or axon and facilitates the transmission of nerve impulses. myeloid cells -- any of the white blood cell (leukocyte) types that do not fall into the lymphocyte category. myelomeningocele -- Type of spina bifida that occurs when the spinal cord and its covering protrude from the opening in the spine. The meninges and spinal nerves come through the open part of the spine. This is the most serious type of spina bifida, which causes nerve damage and more severe disabilities. Effects may include muscle weakness or paralysis below the area of the spine where the incomplete closure (or cleft) occurs, loss of sensation below the cleft, and loss of bowel and bladder control. In addition, fluid may build up and cause an accumulation of fluid in the brain (hydrocephalus). A large number of children born with myelomeningocele also have hydrocephalus; see meningomyelocele. myeloschisis -- a developmental defect characterized by a cleft spinal cord that results from failure of the neural plate to fuse and form a complete neural tube. myelosuppression -- the inhibition of the process of production of blood cells and platelets in the bone marrow. myocardial infarction -- see heart attack. myocardial necrosis and fibrosis -- heart tissue damaged, becoming fibrous, and portions dying myoclonic seizure (epilepsy) -- Seizures characterized by brief, shock-like muscle contractions, such as jerking or twitching of a muscle. A myoclonic seizure causes abnormal movements on both sides of the body at once. myoclonus -- irregular, involuntary contraction of a muscle. myofibril -- one of the slender threads of a cardiac or skeletal muscle fiber, composed of numerous myofilaments. Also called sarcostyle. myoglobin -- a protein in heart and skeletal muscles. During exercise, the muscles use up any available oxygen. Myoglobin has oxygen attached to it, which provides extra oxygen for the muscle to maintain a high level of activity for a longer period of time. When muscle is damaed, myoglobin is released into the bloodstream. myopathies -- diseases of muscle, usually degenerative. myopia -- nearsightedness; inability to see distant objects clearly; a refractive problem wherein the eyeball is excessively long, focusing light in front of the retina. (See Mount Rushmore, first normal vision, second, with myopia.) myopic degeneration -- an uncommon condition characterized by progressive stretching of the eye that damages the retina, the layer of light-sensitive cells that lines the back of the eye. It commonly occurs during young adulthood with a gradual decrease in central vision. Although central vision may be lost, peripheral vision usually remains unaffected. myosin -- protein necessary for muscle contraction. myotonia -- abnormal rigidity of muscles when voluntary movement is attempted. myotonic dystrophy (Steinart's disease) -- the most prominent feature is myotonia, a form of dystonia involving increased muscular contractibility combined with decreased power to release (e.g., a strong handshake with the inability to release it). Other features include myopathy, dysarthria, ptosis, and frontal balding. The age of onset varies from childhood to adulthood. The congenital form is severe, with neonatal hypotonia, motor delay, intellectual disability, and facial muscle palsy. In the congenital form, feeding difficulties and severe respiratory problems are common. Classic myotonia does not begin until around 10 years of age. Associated complications: cataracts, cardiac conduction abnormalities, diabetes, hypogonadism. Cause: Cytosine-thymine-guanine (CTG) expansion of mutations in the muscle protein kinase gene on chromosome 19q13. Severity varies with the number of CTG repeats. Unaffected people have 5 -- 30 repeat copies. Those with the classical adult form have more than 80 copies, and individuals with the childhood onset form usually have more than 500 copies. The correlation between the number of repeats, severity, and age of onset, however, is not always consistent; autosomal dominant. myringotomy -- the surgical incision of the eardrum. It is usually accompanied by the placement of pressure equalizing tubes to drain fluid from the middle ear. myrmecophobia -- fear of ants myth -- a sacred story told as part of a world view or religious belief system and used to make concrete abstract concepts about cosmic and societal origins. mythological images -- Jung: see archetype. mythology -- a complex network of myths that, taken together, constitute the stories that explain the belief system of a people. myxedema -- thickening and coarsening of the skin caused by hypothyroidism. myxophobia -- fear of slime |
| It's never to late to be what you might have been. -- George Eliot |
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